Master Kush is a strain originally named High Rise, which comes from south Amsterdam. This mostly Indica strain gained popularity in coffee shops there as a unique tetraploid strain. Most cannabis strains are diploid. They have two sets of chromosomes, one from each parent in each cell. Tetraploid strains carry four times the number of haploid chromosomes, making eight sets.Master Kush produces strong, but not overwhelming, euphoria that can leave users in a blissful haze. More experienced users report a rise in creativity and intellectual curiosity.Negative effects may include the usual dry eyes and mouth when Master Kush is smoked. Some patients also experience dizziness, paranoia, and anxiety with higher doses or when Master Kush is consumed as an edible.